CD70 antibody (AA 72-101)

Catalog No. ABIN3030417

This anti-CD70 antibody is a Rabbit Polyclonal antibody detecting CD70 in WB, ELISA and IHC. Suitable for Human.

Quick Overview for CD70 antibody (AA 72-101) (ABIN3030417)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CD70 Antibody

Binding Specificity: AA 72-101

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 72-101 from the human protein was used as the immunogen for this CD70 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CD70 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD70 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

UniProt: P32970

Pathways: Cancer Immune Checkpoints