Ceruloplasmin antibody (AA 121-151)

Catalog No. ABIN3030467

The Rabbit Polyclonal anti-Ceruloplasmin antibody has been validated for WB, IHC, ELISA and FACS. It is suitable to detect Ceruloplasmin in samples from Human and Mouse.

Quick Overview for Ceruloplasmin antibody (AA 121-151) (ABIN3030467)

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ceruloplasmin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-Ceruloplasmin Antibody

Binding Specificity: AA 121-151

Purification: Purified

Immunogen: A portion of amino acids 121-151 from the human protein was used as the immunogen for this Ceruloplasmin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Ceruloplasmin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Ceruloplasmin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Ceruloplasmin

Target: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Alternative Name: Ceruloplasmin

Background: Ceruloplasmin (CP) is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.

UniProt: P00450

Pathways: Transition Metal Ion Homeostasis