BIRC3 antibody (AA 101-131)
BIRC3
Reactivity: Human
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
-
- Target See all BIRC3 Antibodies
- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
- Binding Specificity
- AA 101-131
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 101-131 from the human protein was used as the immunogen for this cIAP2 antibody.
- Isotype
- Ig Fraction
-
- Application Notes
- Titration of the cIAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the cIAP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Target
- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
- Alternative Name
- cIAP2
- Background
- BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.
- UniProt
- Q13489
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
-
You are here:
