Selectin E/CD62e antibody

Catalog No. ABIN3032527

This Rabbit Polyclonal antibody specifically detects Selectin E/CD62e in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Selectin E/CD62e antibody (ABIN3032527)

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Selectin E/CD62e antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Selectin E/CD62e Antibody

Purification: Antigen affinity purified

Immunogen: This E-Selectin antibody was produced from rabbits immunized with a human partial recombinant protein.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the E-Selectin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the E-Selectin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Selectin E/CD62e

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Alternative Name: E-Selectin

Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling