Endoplasmic Reticulum Amyloid Binding Protein (ERAB) (AA 199-235) antibody

Catalog No. ABIN3031270

This Rabbit Polyclonal antibody specifically detects Endoplasmic Reticulum Amyloid Binding Protein (ERAB) in IHC, ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Endoplasmic Reticulum Amyloid Binding Protein (ERAB) (AA 199-235) antibody (ABIN3031270)

Target: Endoplasmic Reticulum Amyloid Binding Protein (ERAB)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Product Details

Binding Specificity: AA 199-235

Cross-Reactivity (Details): Expected species reactivity: Rat, Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 199-235 from the human protein was used as the immunogen for this ERAB antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ERAB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: Endoplasmic Reticulum Amyloid Binding Protein (ERAB)

Background: Endoplasmic Reticulum Amyloid Binding protein is a member of the family of short chain dehydrogenase/reductases, unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ERAB appears to trigger cell stress induced by the amyloid peptide.

UniProt: Q6IBS9