Endoplasmic Reticulum Amyloid Binding Protein (ERAB) (AA 199-235) antibody
-
- Target
- Endoplasmic Reticulum Amyloid Binding Protein (ERAB)
- Binding Specificity
- AA 199-235
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
- Cross-Reactivity (Details)
- Expected species reactivity: Rat, Bovine
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 199-235 from the human protein was used as the immunogen for this ERAB antibody.
- Isotype
- Ig Fraction
-
- Application Notes
- Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the ERAB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Target
- Endoplasmic Reticulum Amyloid Binding Protein (ERAB)
- Background
- Endoplasmic Reticulum Amyloid Binding protein is a member of the family of short chain dehydrogenase/reductases, unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ERAB appears to trigger cell stress induced by the amyloid peptide.
- UniProt
- Q6IBS9
-