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GLI2 antibody (C-Term)

GLI2 Reactivity: Human FACS, IF, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031039
$578.58
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  • Target See all GLI2 Antibodies
    GLI2 (GLI Family Zinc Finger 2 (GLI2))
    Binding Specificity
    • 10
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 45
    • 14
    • 6
    • 2
    • 1
    • 1
    Human
    Host
    • 39
    • 7
    • 2
    Rabbit
    Clonality
    • 46
    • 2
    Polyclonal
    Conjugate
    • 18
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    This GLI2 antibody is un-conjugated
    Application
    • 16
    • 16
    • 9
    • 5
    • 4
    • 2
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogen
    This GLI2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1287-1321 amino acids from the C-terminal region of human GLI2.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the GLI2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
    1. GLI-2 exists as five alternatively spliced isoforms of 133 kDa (isoform 1), 132 (2), 88 (3), 86 (4) and 168 kDa (isoform 5).\. Immunofluorescence: 1:25,Flow Cytometry: 1:25,Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the GLI2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    GLI2 (GLI Family Zinc Finger 2 (GLI2))
    Alternative Name
    GLI2 (GLI2 Products)
    Synonyms
    HPE9 antibody, THP1 antibody, THP2 antibody, GLI2/GLI4 antibody, GLI3 antibody, AW546128 antibody, GLI family zinc finger 2 antibody, GLI-Kruppel family member GLI2 antibody, GLI2 antibody, Gli2 antibody
    Background
    Acts as a transcriptional activator. May play a role during embryogenesis. Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1. Is involved in the smoothened (SHH) signaling pathway.
    UniProt
    P10070
    Pathways
    Hedgehog Signaling, Dopaminergic Neurogenesis
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