Histone H3.3 antibody (AA 1-30)

Catalog No. ABIN3031134

This anti-Histone H3.3 antibody is a Rabbit Polyclonal antibody detecting Histone H3.3 in ELISA and DB. Suitable for Human.

Quick Overview for Histone H3.3 antibody (AA 1-30) (ABIN3031134)

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H3.3 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-Histone H3.3 Antibody

Binding Specificity: AA 1-30

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from human H3F3A was used as the immunogen for this Histone H3.3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Histone H3.3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Histone H3.3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Histone H3.3

Target: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Alternative Name: Histone H3.3 (H3F3A)

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

UniProt: P84243