HMGA2 antibody (AA 64-92)

Catalog No. ABIN3031201

This Rabbit Polyclonal antibody specifically detects HMGA2 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for HMGA2 antibody (AA 64-92) (ABIN3031201)

Target: HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-HMGA2 Antibody

Binding Specificity: AA 64-92

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 64-92 from the human protein was used as the immunogen for this HMGA2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the HMGA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HMGA2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for HMGA2

Target: HMGA2 (High Mobility Group AT-Hook 2 (HMGA2))

Alternative Name: HMGA2

Background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P52926

Pathways: Positive Regulation of Response to DNA Damage Stimulus