HOPX antibody (AA 22-54)

Catalog No. ABIN3031254

This anti-HOPX antibody is a Rabbit Polyclonal antibody detecting HOPX in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for HOPX antibody (AA 22-54) (ABIN3031254)

Target: HOPX (HOP Homeobox (HOPX))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HOPX Antibody

Binding Specificity: AA 22-54

Purification: Antigen affinity purified

Immunogen: This mouse Hopx antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of mouse Hopx.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Hopx antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Hopx antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: Hopx

Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.

UniProt: Q8R1H0

Pathways: Regulation of Muscle Cell Differentiation