HOPX antibody (AA 22-54)

Catalog No. ABIN6242849

This Rabbit Polyclonal antibody specifically detects HOPX in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HOPX antibody (AA 22-54) (ABIN6242849)

Target: HOPX (HOP Homeobox (HOPX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB51159

Product Details anti-HOPX Antibody

Binding Specificity: AA 22-54

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Hopx antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of Mouse Hopx.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: Hopx

Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.

Molecular Weight: 8282

UniProt: Q8R1H0

Pathways: Regulation of Muscle Cell Differentiation