HSP90 antibody (AA 150-400)

Catalog No. ABIN3031170

This anti-HSP90 antibody is a Mouse Monoclonal antibody detecting HSP90 in WB and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for HSP90 antibody (AA 150-400) (ABIN3031170)

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP90 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 803CT9-1-2

Product Details anti-HSP90 Antibody

Binding Specificity: AA 150-400

Purification: Purified

Immunogen: A portion of amino acids from 150-400 of the human protein were used as the immunogen for this HSP90 antibody.

Isotype: IgG1 lambda

Application Details

Application Notes: Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS  pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HSP90 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSP90

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Alternative Name: HSP90

Background: Heat Shock Protein 90 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt]

UniProt: P07900

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals