HSP70 1A antibody (AA 574-600)

Catalog No. ABIN3031153

This Mouse Monoclonal antibody specifically detects HSP70 1A in WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for HSP70 1A antibody (AA 574-600) (ABIN3031153)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP70 1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 201CT8-2-3

Product Details anti-HSP70 1A Antibody

Binding Specificity: AA 574-600

Cross-Reactivity (Details): Expected species reactivity: Bovine, Pig

Purification: Purified

Immunogen: A portion of amino acids 574-600 from the human protein was used as the immunogen for this HSPA1A antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Titration of the HSPA1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:2000,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HSPA1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: HSPA1A

Background: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

UniProt: P08107

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process