ICOS antibody (AA 156-185)

Catalog No. ABIN3028725

The Rabbit Polyclonal anti-ICOS antibody (ABIN3028725) specifically detects ICOS in WB, IHC, FACS and ELISA. The antibody is reactive with Human samples.

Quick Overview for ICOS antibody (AA 156-185) (ABIN3028725)

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICOS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Product Details anti-ICOS Antibody

Binding Specificity: AA 156-185

Purification: Purified

Immunogen: A portion of amino acids 156-185 from the human protein was used as the immunogen for this ICOS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ICOS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ICOS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ICOS

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Alternative Name: ICOS

Background: ICOS belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

UniProt: Q9Y6W8

Pathways: Cancer Immune Checkpoints