IGFBP3 antibody (AA 162-189)

Catalog No. ABIN3031352

The Rabbit Polyclonal anti-IGFBP3 antibody has been validated for WB and ELISA. It is suitable to detect IGFBP3 in samples from Human, Mouse and Hamster.

Quick Overview for IGFBP3 antibody (AA 162-189) (ABIN3031352)

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Reactivity: Human, Mouse, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGFBP3 Antibody

Binding Specificity: AA 162-189

Cross-Reactivity (Details): Expected species reactivity: Bovine, Pig

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 162-189 from the human protein was used as the immunogen for this IGFBP3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IGFBP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IGFBP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IGFBP3

Target: IGFBP3 (Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))

Alternative Name: IGFBP3

Background: IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. This protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.

UniProt: P17936

Pathways: Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Growth Factor Binding