IRAK4 antibody (AA 422-449)

Catalog No. ABIN3028767

This anti-IRAK4 antibody is a Rabbit Polyclonal antibody detecting IRAK4 in WB and ELISA. Suitable for Human.

Quick Overview for IRAK4 antibody (AA 422-449) (ABIN3028767)

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRAK4 Antibody

Binding Specificity: AA 422-449

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 422-449 from the mouse protein was used as the immunogen for this Irak4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Irak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Irak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRAK4

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Alternative Name: Irak4

Background: Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).

UniProt: Q8R4K2

Pathways: NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades