IRF4 antibody (AA 164-191)

Catalog No. ABIN3031420

This Rabbit Polyclonal antibody specifically detects IRF4 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for IRF4 antibody (AA 164-191) (ABIN3031420)

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-IRF4 Antibody

Binding Specificity: AA 164-191

Purification: Purified

Immunogen: A portion of amino acids 164-191 from the human protein was used as the immunogen for this IRF4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IRF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IRF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Alternative Name: IRF4

Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

UniProt: Q15306

Pathways: Chromatin Binding