KLF4 antibody (AA 20-53)

Catalog No. ABIN3031573

This Rabbit Polyclonal antibody specifically detects KLF4 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for KLF4 antibody (AA 20-53) (ABIN3031573)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KLF4 Antibody

Binding Specificity: AA 20-53

Purification: Purified

Immunogen: A portion of amino acids 20-53 from the human protein was used as the immunogen for this KLF4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: KLF4

Background: Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance