Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

L1CAM antibody (AA 1154-1182)

L1CAM Reactivity: Human, Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031578
$578.58
Plus shipping costs $45.00
Shipping to: United States
Delivery in 2 to 3 Business Days
  • Target See all L1CAM Antibodies
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    Binding Specificity
    • 16
    • 12
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1154-1182
    Reactivity
    • 112
    • 40
    • 36
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 81
    • 35
    • 2
    Rabbit
    Clonality
    • 71
    • 46
    • 1
    Polyclonal
    Conjugate
    • 56
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This L1CAM antibody is un-conjugated
    Application
    • 59
    • 42
    • 40
    • 29
    • 24
    • 14
    • 13
    • 10
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Rat
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 1154-1182 from the human protein was used as the immunogen for this L1CAM antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the L1CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. Cleavage by ADAM10 results in 180 and 40 kDa bands while cleavage by Plasmin results in 140 and 80 kDa bands.\. Western blot: 1:1000 (1)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the L1CAM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    L1CAM (L1 Cell Adhesion Molecule (L1CAM))
    Alternative Name
    L1CAM (L1CAM Products)
    Synonyms
    l1cam-a antibody, CAML1 antibody, CD171 antibody, HSAS antibody, HSAS1 antibody, MASA antibody, MIC5 antibody, N-CAM-L1 antibody, N-CAML1 antibody, NCAM-L1 antibody, S10 antibody, SPG1 antibody, L1 antibody, Hsas antibody, Hyd antibody, NCAML1 antibody, L1 cell adhesion molecule S homeolog antibody, L1 cell adhesion molecule antibody, l1cam.S antibody, L1CAM antibody, L1cam antibody
    Background
    L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
    UniProt
    P32004
    Pathways
    Synaptic Membrane
You are here:
Support