Lamin B2 antibody (AA 476-504)

Catalog No. ABIN3031589

The Rabbit Polyclonal anti-Lamin B2 antibody is suitable to detect Lamin B2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for Lamin B2 antibody (AA 476-504) (ABIN3031589)

Target: Lamin B2 (LMNB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Lamin B2 Antibody

Binding Specificity: AA 476-504

Purification: Purified

Immunogen: A portion of amino acids 476-504 from the human protein was used as the immunogen for this Lamin B2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Lamin B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Lamin B2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Lamin B2

Target: Lamin B2 (LMNB2)

Alternative Name: Lamin B2

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B2 is one of the two B type proteins, B2.

UniProt: Q03252

Pathways: Apoptosis, Caspase Cascade in Apoptosis