Lactate Dehydrogenase A antibody (AA 204-232)
Quick Overview for Lactate Dehydrogenase A antibody (AA 204-232) (ABIN3031580)
Target
See all Lactate Dehydrogenase A (LDHA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 204-232
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Cross-Reactivity (Details)
- Expected species reactivity: Primate
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 204-232 from the human protein was used as the immunogen for this LDHA antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the LDHA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the LDHA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Lactate Dehydrogenase A (LDHA)
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Alternative Name
- LDHA
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Background
- The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
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UniProt
- P00338
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Pathways
- Warburg Effect
Target
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