LOXL2 antibody (AA 589-617)

Catalog No. ABIN3031668

This anti-LOXL2 antibody is a Rabbit Polyclonal antibody detecting LOXL2 in WB and ELISA. Suitable for Human.

Quick Overview for LOXL2 antibody (AA 589-617) (ABIN3031668)

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LOXL2 Antibody

Binding Specificity: AA 589-617

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Chicken

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 589-617 from the human protein was used as the immunogen for this LOXL2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the LOXL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LOXL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for LOXL2

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Alternative Name: LOXL2

Background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

UniProt: Q9Y4K0

Pathways: Chromatin Binding