MARCKS antibody (AA 241-271)

Catalog No. ABIN3031923

This anti-MARCKS antibody is a Rabbit Polyclonal antibody detecting MARCKS in WB and ELISA. Suitable for Human.

Quick Overview for MARCKS antibody (AA 241-271) (ABIN3031923)

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCKS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MARCKS Antibody

Binding Specificity: AA 241-271

Purification: Purified

Immunogen: A portion of amino acids 241-271 from the human protein was used as the immunogen for this MARCKS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MARCKS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MARCKS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MARCKS

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Alternative Name: MARCKS

Background: MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

UniProt: P29966