MEF2D
Reactivity: Human, Mouse, Rat
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Titration of the MEF2D antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the MEF2D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
MEF2D
(Myocyte Enhancer Factor 2D (MEF2D))
Alternative Name
MEF2D
Background
MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity).