MFN2 antibody (AA 447-476)

Catalog No. ABIN3031818

This anti-MFN2 antibody is a Rabbit Polyclonal antibody detecting MFN2 in WB, IHC, ELISA and FACS. Suitable for Human.

Quick Overview for MFN2 antibody (AA 447-476) (ABIN3031818)

Target: MFN2 (Mitofusin 2 (MFN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MFN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-MFN2 Antibody

Binding Specificity: AA 447-476

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 447-476 from the human protein was used as the immunogen for this MFN2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MFN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MFN2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MFN2

Target: MFN2 (Mitofusin 2 (MFN2))

Alternative Name: MFN2

Background: MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system.

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development