MAP4K4 antibody (AA 618-649)
Quick Overview for MAP4K4 antibody (AA 618-649) (ABIN3031854)
Target
See all MAP4K4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 618-649
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Purification
- Purified
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Immunogen
- A portion of amino acids 618-649 from the human protein was used as the immunogen for this NIK antibody.
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Isotype
- Ig Fraction
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anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibody
MAP4K4 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 4A5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 866-1104) antibodyMAP4K4 Reactivity: Human WB, ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) antibodyMAP4K4 Reactivity: Human WB, FACS Host: Rabbit Monoclonal 25GB1895 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibodyMAP4K4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2D4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 287-336) antibodyMAP4K4 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig, Bat, Chicken, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 400-500) antibodyMAP4K4 Reactivity: Human ELISA Host: Mouse Monoclonal 4H9E7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (N-Term) antibodyMAP4K4 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibodyMAP4K4 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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Application Notes
- Titration of the NIK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the NIK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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Alternative Name
- NIK (Nck-Interacting Kinase)
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Background
- HGK/NIK, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK/NIK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
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UniProt
- O95819
Target
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