NRF1 antibody (AA 226-255)
Quick Overview for NRF1 antibody (AA 226-255) (ABIN3032068)
Target
See all NRF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 226-255
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Zebrafish
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 226-255 from the human protein was used as the immunogen for this NRF1 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the NRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the NRF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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Alternative Name
- NRF1
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Background
- This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
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UniProt
- Q16656
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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