NUP50 antibody (AA 432-461)

Catalog No. ABIN3032078

The Rabbit Polyclonal anti-NUP50 antibody has been validated for WB and ELISA. It is suitable to detect NUP50 in samples from Human and Mouse.

Quick Overview for NUP50 antibody (AA 432-461) (ABIN3032078)

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP50 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NUP50 Antibody

Binding Specificity: AA 432-461

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Purified

Immunogen: A portion of amino acids 432-461 from the human protein was used as the immunogen for this NUP50 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NUP50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NUP50 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Alternative Name: NUP50

Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.

UniProt: Q9UKX7

Pathways: Tube Formation