PCSK4 antibody (AA 168-196)

Catalog No. ABIN3032334

The Rabbit Polyclonal anti-PCSK4 antibody (ABIN3032334) specifically detects PCSK4 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for PCSK4 antibody (AA 168-196) (ABIN3032334)

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PCSK4 Antibody

Binding Specificity: AA 168-196

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 168-196 from the human protein was used as the immunogen for this PCSK4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PCSK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PCSK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PCSK4

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Alternative Name: PCSK4

Background: Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR, MIM 136950), and PACE4 (MIM 167405). Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]).[supplied by OMIM].

UniProt: Q6UW60