FOXP3 antibody (pSer418)

Catalog No. ABIN3028665

This anti-FOXP3 antibody is a Rabbit Polyclonal antibody detecting FOXP3 in ELISA and DB. Suitable for Human.

Quick Overview for FOXP3 antibody (pSer418) (ABIN3028665)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-FOXP3 Antibody

Binding Specificity: pSer418

Cross-Reactivity (Details): Expected species reactivity: Primate

Purification: Antigen affinity purified

Immunogen: This phospho-FOXP3 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS418 of human FOXP3.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-FOXP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-FOXP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FOXP3

Background: The protein is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation