ILK antibody (pThr173)

Catalog No. ABIN3031389

This anti-ILK antibody is a Rabbit Polyclonal antibody detecting ILK in ELISA and DB. Suitable for Human.

Quick Overview for ILK antibody (pThr173) (ABIN3031389)

Target: ILK (Integrin-Linked Kinase (ILK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ILK antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-ILK Antibody

Binding Specificity: pThr173

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine

Purification: Antigen affinity purified

Immunogen: This phospho-ILK antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT173 of human ILK.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-ILK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-ILK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ILK

Target: ILK (Integrin-Linked Kinase (ILK))

Alternative Name: ILK

Background: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration