KLF4 antibody (pSer245)

Catalog No. ABIN3031568

The Rabbit Polyclonal anti-KLF4 antibody is suitable to detect KLF4 in samples from Human. It has been validated for ELISA, IF and DB.

Quick Overview for KLF4 antibody (pSer245) (ABIN3031568)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Dot Blot (DB)

Product Details anti-KLF4 Antibody

Binding Specificity: pSer245

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: This phospho-KLF4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS245 of human KLF4.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: KLF4

Background: Krueppel-like factor family members are involved in growth regulation and a wide range of developmental processes. KLF4 is highly expressed in epithelial tissues including skin and stomach/intestine. Studies have shown that it can function as both an oncogene, upregulating hSSC, and a tumor suppressor, down-regulating colorectal cancer.

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance