NFAT1 antibody (pSer330)

Catalog No. ABIN3029744

The Rabbit Polyclonal anti-NFAT1 antibody has been validated for ELISA and DB. It is suitable to detect NFAT1 in samples from Human.

Quick Overview for NFAT1 antibody (pSer330) (ABIN3029744)

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFAT1 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-NFAT1 Antibody

Binding Specificity: pSer330

Purification: Antigen affinity purified

Immunogen: This phospho-NFATC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS330 of human NFATC2.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-NFATC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-NFATC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NFAT1

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Alternative Name: NFATC2

Background: NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family. It is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response.

UniProt: Q13469

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, VEGF Signaling, BCR Signaling