ULK1 antibody (pSer556)

Catalog No. ABIN3029448

This anti-ULK1 antibody is a Rabbit Polyclonal antibody detecting ULK1 in ELISA, DB and IF. Suitable for Human.

Quick Overview for ULK1 antibody (pSer556) (ABIN3029448)

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK1 antibody is un-conjugated

Application: ELISA, Dot Blot (DB), Immunofluorescence (IF)

Product Details anti-ULK1 Antibody

Binding Specificity: pSer556

Purification: Antigen affinity purified

Immunogen: This phospho-ULK1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS556 of human ULK1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-ULK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:200,Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-ULK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ULK1

Target: ULK1 (Unc-51 Like Kinase 1 (ULK1))

Alternative Name: ULK1

Background: Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity). [UniProt]

UniProt: O75385

Pathways: Regulation of Cell Size, Autophagy