SMC2
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
Titration of the SMC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the SMC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
SMC2
(Structural Maintenance of Chromosomes 2 (SMC2))
Alternative Name
SMC2
Background
SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.