SUMO2 antibody (AA 63-93)

Catalog No. ABIN3032648

The Rabbit Polyclonal anti-SUMO2 antibody has been validated for WB, ELISA and IHC. It is suitable to detect SUMO2 in samples from Human.

Quick Overview for SUMO2 antibody (AA 63-93) (ABIN3032648)

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SUMO2 Antibody

Binding Specificity: AA 63-93

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig, Primate, Chicken, Zebrafish, Hamster, Xenopus

Purification: Purified

Immunogen: A portion of amino acids 63-93 from the human protein was used as the immunogen for this SUMO2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SUMO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SUMO2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SUMO2

Target: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Alternative Name: SUMO2

Background: SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.

UniProt: P61956

Pathways: Methionine Biosynthetic Process