SUMO4 antibody

Catalog No. ABIN3032653

This Rabbit Polyclonal antibody specifically detects SUMO4 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for SUMO4 antibody (ABIN3032653)

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SUMO4 Antibody

Purification: Antigen affinity purified

Immunogen: This SUMO4 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human SUMO4.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SUMO4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SUMO4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SUMO4

Target: SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))

Alternative Name: SUMO4

Background: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. [UniProt]

UniProt: Q6EEV6