SUMO4 antibody
Quick Overview for SUMO4 antibody (ABIN7270372)
Target
See all SUMO4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- SUMO4 Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human SUMO4
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- SUMO4 (Small Ubiquitin Related Modifier 4 (SUMO4))
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Alternative Name
- SUMO4
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Background
- This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008],IDDM5, SMT3H4, SUMO-4, dJ281H8.4,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Mitochondrial metabolism,NF-kB Signaling Pathway,Transcription Factors,Ubiquitin,SUMO4
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Molecular Weight
- 15kDa
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Gene ID
- 387082
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UniProt
- Q6EEV6
Target
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