tau antibody (AA 677-707)

Catalog No. ABIN3031796

The Rabbit Polyclonal anti-tau antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect tau in samples from Human.

Quick Overview for tau antibody (AA 677-707) (ABIN3031796)

Target: tau (tau Protein)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-tau Antibody

Binding Specificity: AA 677-707

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine

Purification: Purified

Immunogen: A portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TAU antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TAU antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for tau

Target: tau (tau Protein)

Alternative Name: tau

Background: TAU/MAPT promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [UniProt]

UniProt: P10636