TRAF4 antibody (AA 427-455)

Catalog No. ABIN3029152

This Rabbit Polyclonal antibody specifically detects TRAF4 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TRAF4 antibody (AA 427-455) (ABIN3029152)

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRAF4 Antibody

Binding Specificity: AA 427-455

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 427-455 from the human protein was used as the immunogen for this TRAF4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TRAF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TRAF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4

Background: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.

UniProt: Q9BUZ4