CD40 Ligand antibody (AA 33-62)

Catalog No. ABIN3028551

This anti-CD40 Ligand antibody is a Rabbit Polyclonal antibody detecting CD40 Ligand in WB, FACS, IHC, ELISA and IF. Suitable for Human.

Quick Overview for CD40 Ligand antibody (AA 33-62) (ABIN3028551)

Target: CD40 Ligand (CD40LG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD40 Ligand antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CD40 Ligand Antibody

Binding Specificity: AA 33-62

Cross-Reactivity (Details): Expected species reactivity: Bovine, Pig

Purification: Purified

Immunogen: A portion of amino acids 33-62 from the human protein was used as the immunogen for this TRAP antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TRAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TRAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD40 Ligand

Target: CD40 Ligand (CD40LG)

Alternative Name: TRAP (CD40L)

Background: TRAP is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in its gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.

UniProt: P29965

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints