TRAP1
Reactivity: Human
WB, IF
Host: Mouse
Polyclonal
unconjugated
Application Notes
Titration of the TRAP-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the TRAP-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
TRAP1
(TNF Receptor-Associated Protein 1 (TRAP1))
Alternative Name
TRAP-1 (HSP75)
Background
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (HSP90AA1) and endoplasmic reticulum (HSP90B1).