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Ubiquitin antibody (AA 36-66)

Ub Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029420
  • Target See all Ubiquitin (Ub) Antibodies
    Ubiquitin (Ub)
    Binding Specificity
    • 18
    • 8
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-66
    Reactivity
    • 145
    • 73
    • 72
    • 67
    • 20
    • 17
    • 17
    • 16
    • 16
    • 16
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 97
    • 73
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 92
    • 83
    Polyclonal
    Conjugate
    • 78
    • 12
    • 11
    • 10
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ubiquitin antibody is un-conjugated
    Application
    • 159
    • 83
    • 83
    • 59
    • 57
    • 46
    • 26
    • 21
    • 19
    • 13
    • 13
    • 9
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    Cross-Reactivity (Details)
    Expected species reactivity: Bovine, C. elegans, Chicken, Drosophila, Mouse, Pig, Primate, Rat,Yeast
    Purification
    Purified
    Immunogen
    A portion of amino acids 36-66 from the human protein was used as the immunogen for this Ubiquitin antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product Ub Primary Antibody
  • Application Notes
    Titration of the Ubiquitin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Ubiquitin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Ubiquitin (Ub)
    Alternative Name
    Ubiquitin (Ub Products)
    Background
    This gene encodes Ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
    UniProt
    P0CG48
    Pathways
    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
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