Cadherin 5 antibody (AA 106-134)

Catalog No. ABIN3030247

This Rabbit Polyclonal antibody specifically detects Cadherin 5 in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for Cadherin 5 antibody (AA 106-134) (ABIN3030247)

Target: Cadherin 5 (CDH5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-Cadherin 5 Antibody

Binding Specificity: AA 106-134

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 106-134 from the human protein was used as the immunogen for this VE Cadherin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the VE Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the VE Cadherin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: VE Cadherin (CDH5)

Background: CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2