XIAP antibody (AA 1-30)
-
- Target See all XIAP Antibodies
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
-
Binding Specificity
- AA 1-30
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This XIAP antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Purified
- Immunogen
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this XIAP antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product XIAP Primary Antibody
-
-
- Application Notes
- Titration of the XIAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the XIAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
- Target
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
- Alternative Name
- XIAP (XIAP Products)
- Background
- BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
- UniProt
- P98170
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
-