C1q
Reactivity: Human
ID, IEP, RID
Host: Goat
Polyclonal
unconjugated
Application Notes
Dilution for WB: 1:100
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute with 1 mL deionized water
Buffer
PBS, pH 7.14
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Target
C1q
(Complement Fragment C1q (C1q))
Alternative Name
Complement C1q
Background
Detection of C1q in serum, in serum-C1 and within immune complexes, inhibits hemolytic activity of C1 by binding to C1q in the liquid phase (antibody concentration necessary to inhibit 50 % of hemolytic activity in the fluid phase is 0.85 μg/mL). With C1 bound to immune complexes a dose dependent increase of C1 activity was observed at antibody concentrations of 1.5 μg/mL. Useful for detection of C1q-bearing immune complexes in patients with rheumatic disorders.