MVP antibody

Catalog No. ABIN4956483

The Mouse Monoclonal anti-MVP antibody (Clone 5A6) (ABIN4956483) specifically detects MVP in WB, IHC, FACS and LBA. The antibody is reactive with Human samples.

Quick Overview for MVP antibody (ABIN4956483)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MVP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Ligand Binding Assay (LBA)

Clone: 5A6

Product Details anti-MVP Antibody

Cross-Reactivity: Human, Rat (Rattus), Mouse (Murine), Rabbit, Hamster

Purification: purified

Immunogen: human LRP

Isotype: IgG2b

Application Details

Application Notes: Dilution for IHC: 1:20

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL deionized water

Buffer: PBS, pH 7.48

Storage: 4 °C/-20 °C

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: LRP

Background: 5A6 specifically reacts with the 85 kD b-chain of human LRP/a2MR which is expressed in a restricted spectrum of cell types. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91). Neutralizing effects of 5A6 have also been reported.