Nuclear Coactivator Protein (p100) (C-Term) antibody

Catalog No. ABIN4956502

This Guinea Pig Polyclonal antibody specifically detects Nuclear Coactivator Protein (p100) in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Nuclear Coactivator Protein (p100) (C-Term) antibody (ABIN4956502)

Target: Nuclear Coactivator Protein (p100)

Reactivity: Human

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details

Binding Specificity: C-Term

Cross-Reactivity: Cow (Bovine), Fruit Fly (Drosophila melanogaster), Human, Rat (Rattus), Mouse (Murine)

Immunogen: synthetic duplicated C-terminus of human p100 protein

Application Details

Application Notes: Dilution for IHC: 1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: serum

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Target Details

Target: Nuclear Coactivator Protein (p100)

Alternative Name: p100 nuclear coactivator protein

Background: P100 is a ubiquitously expressed protein highly conserved during evolution, enhancing e.g. transciptional activity of EBNA2 of EBV, bridging STAT6 with the basal transcription machinery, also described as a part of the RNA polymerase II holoenzyme. The antiserum localized p100 also in the ER and lipid droplets of milk secreting cells. In addition to the nuclear localization the protein was also detected in cytosolic fractions from lactating mammary gland, in storage lipid droplets from adipocytes and in ER from liver.