RORC antibody

Catalog No. ABIN4966337

The Rabbit Polyclonal anti-RORC antibody has been validated for WB. It is suitable to detect RORC in samples from Arabidopsis thaliana.

Quick Overview for RORC antibody (ABIN4966337)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reactivity: Arabidopsis thaliana

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RORC Antibody

Cross-Reactivity (Details): Not reactive in: Chlamydomonas reinhardtii

Predicted Reactivity: Glycine max, Oryza sativa, Physcomitrella patens, Populus trichocarpa, Setaria italica, Sorghum bicolor, Zea mays, Vitis vinifera

Immunogen: KLH-conjugated synthetic peptide derived from Arabidopsis thaliana TOR protein sequence, UniProt: Q9FR53, TAIR: AT1G50030

Application Details

Application Notes: 1 : 5000 with standard ECL (WB)

Comment:

TOR is a subjected to post-translational modifications (ubiquitination and phosphorylation), which can change the migration pattern in SDS gel.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μL of sterile water.

Storage: -20 °C

Storage Comment: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Target Details for RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Alternative Name: Target of rapamycin (TOR)

Background: TOR (Target of rapamycin) is an essential cell growth regulator that controls development from early embryo to seed production in response to nutrient availability in envoronmental stress conditions. It belongs to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR is expressed in embryos, endosperm and meristems. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.

Molecular Weight: 279 kDa

UniProt: Q9FR53

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway