Lamin B2 antibody (C-Term)

Catalog No. ABIN497969

The Rabbit Polyclonal anti-Lamin B2 antibody has been validated for WB and EIA. It is suitable to detect Lamin B2 in samples from Human.

Quick Overview for Lamin B2 antibody (C-Term) (ABIN497969)

Target: Lamin B2 (LMNB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Lamin B2 Antibody

Binding Specificity: AA 483-512, C-Term

Specificity: Recognizes Lamin B2 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Lamin B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of Human Lamin B2. Genename: LMNB2

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000Western blotting: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Lamin B2

Target: Lamin B2 (LMNB2)

Alternative Name: Lamin-B2 (LMNB2)

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B2 is one of the two B type proteins, B2.Synonyms: LMN2, LMNB, LMNB-2, LMNB2, Lamin-B2, Nuclear Envelope Marker

Gene ID: 84823

NCBI Accession: NP_116126

UniProt: Q03252

Pathways: Apoptosis, Caspase Cascade in Apoptosis