RBM5 antibody
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- Target See all RBM5 Antibodies
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RBM5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of LUCA15 protein. (region surrounding asn261)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product RBM5 Primary Antibody
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- Application Notes
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
- Alternative Name
- RBM5 / LUCA15 (RBM5 Products)
- Synonyms
- wu:fc25a08 antibody, wu:fe06f12 antibody, g15 antibody, h37 antibody, luca15 antibody, rbm5 antibody, rmb5 antibody, RBM5 antibody, G15 antibody, LUCA15 antibody, RMB5 antibody, D030069N10Rik antibody, RNA binding motif protein 5 antibody, RNA binding motif protein 5 S homeolog antibody, RNA binding motif protein 5 L homeolog antibody, rbm5 antibody, rbm5.S antibody, RBM5 antibody, rbm5.L antibody, Rbm5 antibody
- Background
- DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similiar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.Synonyms: NY-REN-9, Putative tumor suppressor LUCA15, RNA-binding motif protein 5, RNA-binding protein 5, Renal carcinoma antigen NY-REN-9
- Molecular Weight
- approx. 92 kDa
- Gene ID
- 10181
- NCBI Accession
- NP_005769
- UniProt
- P52756
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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